Fidelis is a free-standing international institute, operating in conjunction with affiliated institutes at various institutions and universities in the USA, Mexico, Chile, Spain and Italy. The founding partner and first affiliate is the Regina Apostolorum Athenaeum in Rome.

Regina Apostolorum itself was founded in 1993 with the mission of providing education ordered toward Christian leadership and promoting research aimed at imbuing society with the spirit of Christ. The athenaeum at present consists of three faculties: Philosophy, Theology, and Bioethics. It grants bachelors, licentiate (masters), and doctoral degrees in each.

Fidelis International Institute has agreements with the following educational institutions in the following countries: